Pfizer Q2 2026 Earnings: Beats Estimates, Raises Revenue Guidance Despite Impairment-Driven GAAP Loss

Pfizer's adjusted profit and revenue beat Wall Street estimates and it raised its 2026 revenue outlook, even as a large drug-impairment charge pushed it to a GAAP net loss for the quarter.

Q2 2026ReportedExpectedSurprise
EPS$0.77$0.69+11.4%
Revenue$15.03B$14.55B+3.3%

Key takeaways

  • Adjusted profit and revenue both topped Wall Street’s forecasts, extending Pfizer’s recent streak of beating estimates on both lines.
  • Despite the adjusted beat, Pfizer posted a GAAP net loss for the quarter because of a $4.3 billion non-cash write-down — mostly a $3.8 billion charge tied to a cancer-drug candidate (sigvotatug vedotin) after disappointing late-stage trial results. It’s an accounting adjustment, not a cash cost, so it doesn’t affect guidance or the dividend.
  • Growth is increasingly coming from newer medicines rather than COVID products: revenue from recently launched and acquired drugs rose sharply and blood-thinner Eliquis remained a top seller, while Paxlovid sales fell about 95% and Comirnaty vaccine sales dropped roughly a third as COVID infections and demand keep declining.
  • Pfizer raised the low end of its full-year 2026 revenue outlook to $60.5-$62.5 billion (from $59.5-$62.5 billion), citing roughly $1.5 billion of expected upside from non-COVID products, partly offset by a weaker COVID-treatment sales forecast.
  • Full-year adjusted profit guidance was held at $2.80-$3.00 per share; that range already bakes in about a $0.10-per-share hit expected next quarter from a recently closed oncology licensing deal with Innovent Biologics.
  • CEO Albert Bourla said Pfizer “had another strong quarter, delivering on our financial commitments,” pointing to momentum in the company’s obesity-drug program and continued strength in its cancer-drug portfolio.
  • Looking at the trailing twelve months, Pfizer keeps about 75 cents of every revenue dollar after production costs (gross margin), but only about 15 cents after all operating expenses like R&D and sales costs — showing how much the company spends beyond manufacturing to bring drugs to market. Per-share earnings over that same period are still down roughly 5% from a year earlier, reflecting charges like this quarter’s impairment even as revenue has grown only modestly.

Q2 2026 in context

MetricJun 2026Jun 2025Change
Revenue$15.0B$14.7B+2.6%
Net income-$248M$2.9B-108.5%
Free cash flow$302M-$1.2B+125.2%
Diluted EPS-$0.04$0.51-107.8%
Gross margin72.8%74.2%-1.4 pts
Net margin-1.6%19.9%-21.5 pts

Figures for the quarter ended Jun 2026 and the quarter ended Jun 2025, as reported to the SEC.

Pfizer Inc revenue, same quarter each year
$13.3BJun 2024$14.7BJun 2025$15.0BJun 2026
Pfizer Inc quarterly revenue through Jun 2026
$17.7BSep 2024$17.8BDec 2024$13.7BMar 2025$14.7BJun 2025$16.7BSep 2025$17.6BDec 2025$14.5BMar 2026$15.0BJun 2026

How the stock took it

Pfizer Inc closed at $25.03 on Aug 3, 2026, the last session before the report, and at $25.81 on Aug 5, 2026, the first session after it — +3.1% across the report.

Earlier reportClose beforeClose afterChange
May 5, 2026$26.30$26.53+0.9%
Nov 4, 2025$24.66$24.61-0.2%

Closes from the market's daily record. Each figure spans the report date — from the last session that closed before it to the first that closed after — because a company may report before the open or after the close.

Fundamentals

MetricValuePeriod
Gross margin74.8%Trailing 12 months
Operating margin15.4%Trailing 12 months
Net profit margin11.8%Trailing 12 months
Pretax margin12.5%Trailing 12 months
EPS$1.31Trailing 12 months
Revenue growth (YoY)1.4%Trailing 12 months
EPS growth (YoY)-5.3%Trailing 12 months
Return on equity8.4%Trailing 12 months

Financial history →

Sources: company report · publication (Yahoo Finance) · publication (TechTimes) · earnings call

This content is for informational purposes only and is not investment advice. Always do your own research before making financial decisions.