Bristol-Myers Squibb Q1 2026 earnings: newer drugs offset declines in older ones

BMS posted roughly flat quarterly revenue as newer medicines grew and older ones softened; the company reaffirmed its full-year 2026 outlook.

Q1 2026Reported
EPS$1.31
Revenue$11.49B

Figures as reported by the company to the SEC for the quarter ended March 31, 2026. Analyst estimates are not part of a filing, so no comparison to expectations is shown.

Key takeaways

  • Total revenue for the quarter was about flat compared with a year earlier, as growth in newer medicines helped offset declines in some older ones. The company’s “growth portfolio” — newer drugs including Reblozyl, Breyanzi, Camzyos, Opdualag, Qvantig and the newly launched Cobenfy — rose 9% to roughly $6.2 billion.
  • Eliquis, BMS’s blood-thinner and still one of its biggest products, grew about 13% to roughly $4.1 billion. Management noted some of that increase reflects distributors stocking up ahead of a U.S. price change, an effect it expects to unwind in the current quarter.
  • Opdivo, the company’s cancer immunotherapy, saw revenue decline around 8% to about $2.1 billion, which the company attributed largely to distributors drawing down inventory in the U.S. rather than a fall in underlying patient demand.
  • Camzyos, a heart-disease drug, nearly doubled in sales to $314 million, while Cobenfy, a newer schizophrenia treatment, brought in $56 million and continues to build from a small base.
  • Bristol-Myers Squibb reaffirmed its full-year 2026 targets: total revenue of roughly $46.0 billion to $47.5 billion and full-year adjusted earnings per share of $6.05 to $6.35, saying both are trending toward the higher end of those ranges.
  • Trailing-twelve-month gross margin stood at about 71.7% and operating margin at about 25.5%, reflecting a business model where most revenue comes from patent-protected drugs that are costly to develop but comparatively cheap to manufacture once approved.
  • Earnings per share over the trailing twelve months roughly doubled from a year earlier, a comparison that reflects the prior-year period including unusually large one-time charges (such as costs tied to acquisitions and restructuring) rather than a simple doubling of underlying profitability.
  • Management pointed to several late-stage clinical trial results expected later in 2026 as near-term catalysts to watch, including milvexian (a blood-thinner) in atrial fibrillation and stroke prevention, Cobenfy in Alzheimer’s-related psychosis, admilparant in a lung disease called IPF, and further data on iberdomide.

Q1 2026 in context

MetricMar 2026Mar 2025Change
Revenue$11.5B$11.2B+2.6%
Net income$2.7B$2.5B+9.0%
Free cash flow$757M$1.7B-55.3%
Diluted EPS$1.31$1.20+9.2%
Gross margin70.2%72.9%-2.7 pts
Net margin23.3%21.9%+1.4 pts

Figures for the quarter ended Mar 2026 and the quarter ended Mar 2025, as reported to the SEC.

Bristol-Myers Squibb Co revenue, same quarter each year
$11.9BMar 2024$11.2BMar 2025$11.5BMar 2026
Bristol-Myers Squibb Co quarterly revenue through Mar 2026
$12.2BJun 2024$11.9BSep 2024$12.3BDec 2024$11.2BMar 2025$12.3BJun 2025$12.2BSep 2025$12.5BDec 2025$11.5BMar 2026

How the stock took it

Bristol-Myers Squibb Co closed at $57.59 on Apr 29, 2026, the last session before the report, and at $58.22 on May 1, 2026, the first session after it — +1.1% across the report.

Earlier reportClose beforeClose afterChange
Oct 30, 2025$42.60$46.07+8.2%

Closes from the market's daily record. Each figure spans the report date — from the last session that closed before it to the first that closed after — because a company may report before the open or after the close.

Financial history →

Sources: company report · earnings call

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